Solved by a verified expert:Case Assignment
In the Module 4 Case assignment you will have the opportunity to explore
the new era of personalized medicine that uses genetic mapping to determine
medical treatment. Watch the NOVA video:Cracking Your Genetic Code to learn more about the genetic
technology available to us and what it means for medicine, ethics, and the
future of human society.
After watching this video, proceed to the following resource and address
the topics below in a 2-3 page paperhttp://www.nature.com/scitable/topicpage/genetic-mutation-1127
1. Explain what a
genetic mutation is and the difference between inherited mutations versus point
mutations.
2. Describe how the
technology explained in “Cracking Your Genetic Code” can be used to
detect mutations and predict your health.
3. Form an opinion on
whether or not you support utilizing genetic mapping to develop personalized
medical treatment. Find evidence to support your opinion and cite your
sources. What dangers do you see dangers in knowing our personal genome?
Assignment Expectations
This paper should be approximately 2-3 pages long and reflect the
information contained in the resources provided above. When summarizing
the information you read from the Nature website, NOVA video, or any resources
you use to support your opinions, be sure to synthesize the information into
your own words, and cite the references. Please use complete
sentences and write your paper in essay format using subheadings to organize
the required topics.
Module 4 – SLP
GENETICS AND HEREDITY
Overview
For the Module 4 SLP, you will
build on your understanding of the structure of DNA, genetics, and inheritance
by exploring some applied genetic engineering techniques. You will review
the three papers you have read on the Deepwater Horizon Spill:
Biello D (2010)Clean Up
the Deepwater Horizon Oil Spill. Scientific America: May 25,
2010.
Urakawa, H., Garcia, Juan C.,
Barreto, Patricia D., Molina, Gabriela A., Barreto, Jose C. (2012).A
sensitive crude oil bioassay indicates that oil spills potentially induce a
change of major nitrifying prokaryotes from the Archaea to the Bacteria.Environmental Pollution.
164:42-45
Byrd D (2014)How oil
spill chemicals cause heart failure in fish.EarthSky Feb 18, 2014.
and consider the effects of
toxicity on representative members from three domains:
Archaea -Nitrosopumilus maritimus
Bacteria -Nitrosococcus oceani
Eukarya -Thunnus
thynnus(Atlantic Bluefin Tuna)
In order to make connections
between the results found in these studies, assess the damage caused by the
Deepwater Horizon Oil Spill and move forward in your analysis on how best to
remediate the spill.
After analyzing these studies
in various assignments in the previous modules, you will now prepare a document
for your Shoreline Assessment Team that describes your first interpretation of
the data and discusses one approach to remediation that involves genetic
engineering.
View these resources to
complete this assignment:
Scientific American Instant
Egghead Video: Can Microbes clean Up Our Oily Mess?
http://www.scientificamerican.com/video/can-microbes-clean-up-our-oily-mess2013-12-11/
Interview with Professor
Barbara Block on BBC News:
http://www.bbc.co.uk/news/science-environment-26184116
Tutorials on Genetic
Engineering
Making a Recombinant Plasmid
http://plantandsoil.unl.edu/pages/animation.php?a=making_a_recombinant_plasmid.swf&b=1003514583
Bacteria Transformationhttp://plantandsoil.unl.edu/pages/animation.php?a=Bacteria_Transformation.swf&b=1003514686
Assignment
Prepare a 3-4 page document
that outlines your analysis of the effects of the Deepwater Spill on study
species in the Gulf of Mexico. In your report include:
Part I – Influence of Crude Oil
onNitrosopumilus maritimusandNitrosococcus
oceani
1.
Which species appeared to be affected by crude oil assays in the
Urakawa et al (2012) study? How were they affected in the study?
2.
Based on what you know about the metabolism of the organisms,
which species was more likely to have been successful in an environment with
abundant hydrocarbons?
Part II – Influence of Crude
Oil onThunnus thynnus(Atlantic Bluefin Tuna)
1.
Provide an overview of the documented effects of crude oil onThunnus
thynnus.
2.
What stage of development is affected and how could this affect
the population?
3.
What economic impact would this have on the area?
4.
What is a “highly conserved gene?” What relationship do
these results have to the effects of hydrocarbons on humans?
Part III –
Recommendations for Remediation
Do you recommend genetically
engineering a prokaryote to remediate this spill? In your assessment provide
reasons for BOTH why and why not this would be a good approach, and describe
which genes would need to be targeted and which species would be better suited
to be transformed -Nitrosopumilus
maritimusorNitrosococcus oceani.
SLP
Assignment Expectations
The Session Long Project consists of an integrative project
emphasizing the personalized application of each module’s concepts. For Modules
1–5, students are required to engage in an original integrative project
reflecting their comprehensive knowledge of and ability to apply the course
materials. Each component of the SLP will be graded on a modular basis.
Your essay is considered a scholarly work. You will be provided
with many scholarly references to begin each assignment. For any additional
research you are required to do to complete your assignment, please use
scholarly references such as a peer reviewed journal article or a government
sponsored or university sponsored website. As you read through your
sources, take notes from your sources and then write your paper in your own
words, describing what you have learned from your research. Direct quotes
should be limited and must be designated by quotation marks. Paraphrased ideas
must give credit to the original author, for example (Murray,
2014). Direct copying from “homework help” websites will not
receive credit.
When you write your essay, please organize your paper to include
an introduction (overview of the assignment), body with subtitles (reflecting
the requirements of the assignment), and a summary (develop connections between
the required topics).
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