Description ANSWER FOLLOWING QUESTIONS MULTIPLE CHOICE 1) Which of the following is not a true statement

  

Description ANSWER FOLLOWING QUESTIONS MULTIPLE CHOICE 1) Which of the following is not a true statement regarding metabolic pathways? a) Metabolic pathways can be regulated genetically by altering expression levels of enzymes in the pathway. b) Metabolic pathways can be regulated allosterically by small molecule products of the pathway. c)Metabolic pathways can be regulated covalently by transient modification or complete proteolysis of enzymes in the pathway. d)Biosynthetic pathways are identical to breakdown pathways but run in reverse. 2)Mg2+ is requirement of all protein kinase enzymes. Which statement below best describes the role played by Mg2+ in a typical kinase enzyme-catalyzed reaction? a)Mg2+ is a metal ion co-factor that is required for the enzyme-catalyzed reaction to occur. b)Mg2+ is a co-substrate co-factor that is required for the enzyme-catalyzed reaction to occur. c)Mg2+ is the substrate that is converted into product during the enzyme-catalyzed reaction d) Mg2+ is a vitamin co-factor that is required for the enzyme-catalyzed reaction to occur. e)Mg2+ is a prosthetic group co-factor that is required for the enzyme-catalyzed reaction to occur. 3) picture attached (#4 in the pic) 4)Given the the standard reduction potentials for cystine disulfide and NAD+ on Table 1 below, calculate the standard state reduction potential for the chemical reaction that follows. Give your answer in Volts to three decimals (thousandths) and do not include units. Table 1. Standard Reduction Potentials of Some Biochemically Important Half-Reactions Half-Reaction ??°’ (V) NAD+ + H+ + 2e- ? NADH -0.315 Cystine disulfide + 2H+ + 2e-? 2 Cysteine -0.340 Cystine disulfide + NADH + H+ ? 2 Cysteine + NAD+ 5)Consider the chemical reaction: ATP + AMP ? 2 ADP Using data in the Table 1 below, calculate the standard state Gibbs Free Energy (?G°’) for this reaction. Give your answer in kJ/mol to one decimal (tenths) without units. Table 1. Standard Free Energies of Phosphate Hydrolysis for Some Compounds of Biological Interest Compound ?G°’ (kJ/mol) ATP (? ADP + Pi) -30.5 ADP (? AMP + Pi) -32.8 6) What is the name of the enzyme that catalyzes the reaction: ATP + AMP ? 2 ADP A) Nucleoside diphosphate kinase B)Ribonuclease C)Adenylate kinase D)Inorganic pyrophosphatase 7) The concentrations of ATP, ADP, and AMP in a particular rat hepatocyte cell are 3.38 mM, 1.32 mM, and 0.29 mM, respectively. Will the reaction ATP + AMP ? 2 ADP favor formation of products (2 ADP) or reactants (ATP + AMP) under the conditions in this rat hepatocyte cell?