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UMUC Biology 102/103
Lab5:Meiosis
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Pre-Lab Questions
What
major event occurs during interphase?
A
person, residing in a location where they are exposed to the sun often,
develops a mutation in some of their skin cells resulting in cancer.
Consider whether their offspring will be born with the same mutation. Use
scientific evidence to support your answer.
Experiment
1: Following Chromosomal DNA Movement through Meiosis
Data Tables and Post-Lab Assessment
Part 1 – Meiotic Division Beads Diagram without Crossing Over
Prophase I
Metaphase
I
Anaphase I
Telophase
I
Prophase
II
Metaphase
II
Anaphase
II
Telophase
II
Cytokinesis
Part 2:Meiotic Division Beads Diagram with Crossing Over
Prophase I
Metaphase
I
Anaphase I
Telophase
I
Prophase
II
Metaphase
II
Anaphase
II
Telophase
II
Cytokinesis
Post-Lab Questions
1. What is the ploidy of the
DNA at the end of meiosis I? What about at the end of meiosis II?
2. How are meiosis I and
meiosis II different?
3. Why do you use non-sister
chromatids to demonstrate crossing over?
4. What combinations of
alleles could result from a crossover between BD and bd chromosomes?
5. How many chromosomes were
present when meiosis I started?
6. How many nuclei are present
at the end of meiosis II? How many chromosomes are in each?
7. Identify two ways that
meiosis contributes to genetic recombination.
8. Why is it necessary to
reduce the number of chromosomes in gametes, but not in other cells?
9. Blue whales have 44
chromosomes in every cell. Determine how many chromosomes you would expect to
find in the following:
Sperm Cell:
Egg Cell:
Daughter Cell from Meiosis I:
Daughter Cell from Meiosis II:
10.
Research
and find a disease that is caused by chromosomal mutations. When does the
mutation occur? What chromosomes are affected? What are the consequences?
11.
Diagram
what would happen if sexual reproduction took place for
four generations using diploid (2n) cells.
Experiment
2: The Importance of Cell Cycle Control
Data
Post-Lab Questions
1.
Record
your hypothesis from Step 1 in the Procedure section here.
2.
What
do your results indicate about cell cycle control?
3.
Suppose
a person developed a mutation in a somatic cell which diminishes the
performance of the body’s natural cell cycle control proteins. This mutation
resulted in cancer, but was effectively treated with a cocktail of
cancer-fighting techniques. Is it possible for this person’s future children to
inherit this cancer-causing mutation? Be specific when you explain why or why
not.
4.
Why
do cells which lack cell cycle control exhibit karyotypes which look physically
different than cells with normal cell cycle.
5.
What
are HeLa cells? Why are HeLa cells appropriate for this experiment?
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