Solved by a verified expert:1.
Define
the term “genetic variation.”
If a
gene or locus has two alleles (A and a) in a population, what are all
the possible genotypes?
If the
frequency of (A) allele = p, and the frequency of (a) allele is q, what
is the frequency of all possible genotypes in this population?
2.
What is
the Hardy-Weinberg equilibrium?
In a
population, a locus A has two alleles (A) and (a). The frequency f of
(A) is f (A) = 0.6; what is the f (a)?
Using
these frequencies, calculate the frequencies of all possible genotypes
in a population in Hardy-Weinberg equilibrium.
3.
In a
population (Z), the frequencies of genotypes of a two allele locus (B
and b) are f(BB) = 0.3, f(bb) = 0.6, f (Bb) = 0.1. Calculate the
frequencies of both alleles.
Using
the allele frequencies calculated in a., calculate the frequencies of
all possible genotypes at this locus in a population after one
generation of random mating.
Is the
population (Z) in part a above in Hardy-Weinberg equilibrium? The
population size is 1000.
4.
Describe
how you would use the Hardy-Weinberg equilibrium to calculate genotype
frequencies of a locus with three alleles.
If the
f(D) of an X-linked gene in a population = 0.8, what is the f(d) of the
other allele at this locus?
What is
the frequency of females’ homozygous for d allele (XdXd)?
What is
the frequency of males’ hemizygous for the d allele (XdY)?
5.
Explain
why more males present with X-linked recessive diseases. Show your
reasoning.
Why must
the five assumptions/criteria apply to a population before we can say it
is in Hardy-Weinberg equilibrium?
Take any
one of these assumptions and explain in detail how it could disrupt the
Hardy-Weinberg equilibrium for a particular gene locus.
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