Expert answer:About 20% of colorectal cancers have mutations in

  

Solved by a verified expert:About 20% of colorectal cancers have mutations in the B-Raf gene, which is a serine/threonine kinase, which mediates cellular response to groth signals. Raf is activated when a phosphate is added to Thr 598 and Ser 601. The mutation in B-Raf found in cancer cells makes it constitutively active and does not need activation via Ras protein which is a requirement for a normal Raf activation. 95% of mutatnt B-Raf gene have glutamate in place of Val 599. Why do you suppose that B-Raf with glutamate at position 599 is active?

How it works

  1. Paste your instructions in the instructions box. You can also attach an instructions file
  2. Select the writer category, deadline, education level and review the instructions 
  3. Make a payment for the order to be assignment to a writer
  4.  Download the paper after the writer uploads it 

Will the writer plagiarize my essay?

You will get a plagiarism-free paper and you can get an originality report upon request.

Is this service safe?

All the personal information is confidential and we have 100% safe payment methods. We also guarantee good grades