Solved by a verified expert:1/Which step of the metastatic cascade do you believe requires the most or least amount of effort/energy by cancer cells? Explain your response.2/ Angiogenesis (generation of new blood vessels) is important for maintaining cardiovascular health but also feeds cancer cells. There are many treatments targeting angiogenesis so that cancer cells will starve. Do you think this strategy is a good idea? Explain your response.3/ which immune cell type do you believe is most important to have? Explain your response.4/ why is it so important to know the tumor stage and grade prior to attempting to treat cancer? Include information on the difference between the terms.